Outcomes of Functional Endoscopic Sinus Surgery (FESS) in Patients with Chronic Rhino Sinusitis with Nasal Polyps

Original Article

Authors

DOI:

https://doi.org/10.69837/pjammr.v3i2.78

Keywords:

Endoscopic Sinus Surgery; Chronic Rhinosinusitis; Nasal Polyps; Treatment Outcome

Abstract

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition characterized by nasal obstruction, olfactory dysfunction, and reduced quality of life. Functional endoscopic sinus surgery (FESS) is the preferred treatment for patients who fail medical therapy; however, recurrence remains a concern.

Objective: To evaluate clinical outcomes, symptom relief, quality-of-life improvement, and recurrence after FESS in patients with CRSwNP.

Methods: This prospective observational study was conducted in the Department of ENT at Khyber Teaching Hospital, Peshawar, Pakistan, from January 2023 to January 2024. A total of 75 patients with CRSwNP were enrolled using consecutive non-probability sampling. All patients underwent FESS. Clinical outcomes were assessed using the Sino-Nasal Outcome Test-22 (SNOT-22), nasal endoscopy, and postoperative follow-up at 3, 6, and 12 months. Primary outcome measures included symptom improvement, quality-of-life changes, recurrence, and postoperative complications. Data were analyzed using SPSS version 24.0. Continuous variables were expressed as mean ± standard deviation, and paired t-tests were used for preoperative and postoperative comparisons. A p-value <0.05 was considered statistically significant.

Results: The mean age was 44.7 ± 12.5 years. Significant improvement in SNOT-22 scores was observed, decreasing from 62.4 ± 9.8 preoperatively to 28.7 ± 7.6 at 12 months (p < 0.001). Nasal congestion resolved in 92% of patients, hyposmia improved in 63%, and headache improved in 62%. Recurrence was observed in 24% of cases. No major complications were reported. Extended FESS showed better outcomes than limited FESS (p = 0.028).

Conclusion: FESS is a safe and effective treatment for CRSwNP, significantly improving symptoms and quality of life. Despite the risk of recurrence, appropriate surgical approach and patient selection enhance long-term outcomes.

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Published

10-07-2025

How to Cite

Tahreem Fatima, Shakir Ullah, Imran khan, Mushtaq Ahmad, Muhammad Afaq, & Osama Nawaz. (2025). Outcomes of Functional Endoscopic Sinus Surgery (FESS) in Patients with Chronic Rhino Sinusitis with Nasal Polyps: Original Article . Pakistan Journal of Advances in Medicine and Medical Research , 3(2), 84–87. https://doi.org/10.69837/pjammr.v3i2.78

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