Impact of Vitamin D Supplementation on HbA1c Levels in Type 2 Diabetes Mellitus Patients with Asymptomatic Vitamin D Deficiency: A Prospective Study.: Original Article

Aftab Khattak; Zia Ullah Khan; Khalid Usman; Tahir Ghaffar

doi:10.69837/pjammr.v3i2.69

Impact of Vitamin D Supplementation on HbA1c Levels in Type 2 Diabetes Mellitus Patients with Asymptomatic Vitamin D Deficiency: A Prospective Study.

Original Article

Authors

Aftab Khattak Consultant Department of Diabetes, Endocrinology & Metabolic diseases, Hayat Abad Medical Complex, Peshawar, Pakistan https://orcid.org/0009-0004-2895-6343
Zia Ullah Khan Consultant Department of Diabetes, Endocrinology & Metabolic diseases, Hayat Abad Medical Complex, Peshawar, Pakistan https://orcid.org/0000-0002-8529-580X
Khalid Usman Associate Professor Department of Diabetes, Endocrinology & Metabolic diseases, Hayat Abad Medical Complex, Peshawar, Pakistan https://orcid.org/0009-0008-3282-430X
Tahir Ghaffar Assistant Professor of Endocrinology, Department of Diabetes, Endocrinology & Metabolic diseases, Hayat Abad Medical Complex, Peshawar, Pakistan. https://orcid.org/0000-0001-7945-2429

DOI:

https://doi.org/10.69837/pjammr.v3i2.69

Keywords:

T2DM, Metformin, HbA1c, Vitamin D supplementation.

Abstract

Background: Vitamin D deficiency is common in patients with type 2 diabetes mellitus (T2DM) and may influence glycemic control.

Objective: To evaluate the effect of vitamin D supplementation on HbA1c levels in T2DM patients with asymptomatic vitamin D deficiency.

Methods: A total of 250 patients were enrolled, of which 128 completed the study. Participants were divided into two groups: Group A (metformin only) and Group B (metformin plus vitamin D supplementation 200,000 IU/month for 3 months). HbA1c and vitamin D levels were assessed at baseline and follow-up. Statistical analysis was performed using SPSS version 20, with p<0.05 considered significant.

Results: A total of 128 patients were analyzed. Group B showed a significant reduction in HbA1c levels compared to Group A (p<0.05). Vitamin D levels increased significantly in the intervention group.

Conclusion: Vitamin D supplementation significantly improves glycemic control in T2DM patients with vitamin D deficiency and may serve as an adjunct to standard therapy.

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Published

10-07-2025

How to Cite

Aftab Khattak, Zia Ullah Khan, Khalid Usman, & Tahir Ghaffar. (2025). Impact of Vitamin D Supplementation on HbA1c Levels in Type 2 Diabetes Mellitus Patients with Asymptomatic Vitamin D Deficiency: A Prospective Study.: Original Article . Pakistan Journal of Advances in Medicine and Medical Research , 3(2), 48–53. https://doi.org/10.69837/pjammr.v3i2.69

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Issue

Vol. 3 No. 2 (2025): PJAMMR;Vol.3.No.2 Jan-June

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Articles

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