Impact Of Vitamin D Supplementation On Hba1c Level In Type 2 Diabetes Mellitus Patients Having Asymptomatic Vitamin D Deficiency In Northern Region Of Khyber Pakhtunkhwa, Pakistan A Prospective interventional Multi Center study.

Original Article

Abstract

 Vitamin D deficiency is linked to recurring and infectious diseases. Recent research has shown that vitamin D has skeleton-related functions, such as the ability to inhibit the development of cancer and cardio metabolic disorders and to have anti-inflammatory characteristics. Vitamin D insufficiency is relatively widespread and may contribute to the pathophysiology of disorders linked to insulin resistance, such as diabetes and obesity.  Possible impacts on Type 2 Diabetes Mellitus (T2DM) patients with asymptomatic vitamin D deficiency's HbA1C levels have been discussed in this study. The study's goal is to find out whether supplementing with vitamin D can lower HbA1C levels in those with T2DM and asymptomatic vitamin D deficiency. To investigate the impact of vitamin D supplementation on HbA1 level in patients with newly diagnosed Type II diabetes who are asymptomatically Vitamin D deficient in northern Khyber Pakhtunkhwa region, Pakistan. The study likely uses a randomized controlled trial (RCT) design, in which two groups of T2DM patients with asymptomatic vitamin D deficiency are given, respectively, placebos and vitamin D supplements. Before and after a predetermined intervention time, the HbA1C levels in both groups are measured.  Both the intervention (vitamin D supplementation) and the control (placebo) groups' participant demographic and clinical characteristics, such as age, gender, diabetes duration, baseline HbA1C levels, and vitamin D levels, were described. The main result demonstrated the effect of vitamin D supplementation on HbA1C levels, and differences in HbA1C levels between the two groups were statistically significant after the intervention. This could include modifications to mean HbA1C values and any variations in the proportion.